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Structural insights into RNA recognition and activation of RIG-I-like receptors

RIG-I like receptors (RLR) that recognize non-self RNA play critical roles in activating host innate immune pathways in response to viral infections. Not surprisingly, RLRs and their associated signaling networks are also targeted by numerous antagonists that facilitate viral pathogenesis. Although...

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Detalles Bibliográficos
Autores principales: Leung, Daisy W, Amarasinghe, Gaya K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383332/
https://www.ncbi.nlm.nih.gov/pubmed/22560447
http://dx.doi.org/10.1016/j.sbi.2012.03.011