Do human transposable element small RNAs serve primarily as genome defenders or genome regulators?

It is currently thought that small RNA (sRNA) based repression mechanisms are primarily employed to mitigate the mutagenic threat posed by the activity of transposable elements (TEs). This can be achieved by the sRNA guided processing of TE transcripts via Dicer-dependent (e.g., siRNA) or Dicer-inde...

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Detalles Bibliográficos
Autores principales: Lee, Kevin J., Conley, Andrew B., Lunyak, Victoria V., Jordan, I. King
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383446/
https://www.ncbi.nlm.nih.gov/pubmed/22754749
http://dx.doi.org/10.4161/mge.19031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383446/
https://www.ncbi.nlm.nih.gov/pubmed/22754749
http://dx.doi.org/10.4161/mge.19031

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