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High Avidity Antibodies to Full-Length VAR2CSA Correlate with Absence of Placental Malaria

VAR2CSA mediates sequestration of Plasmodium falciparum-infected erythrocytes in the placenta, increasing the risk of poor pregnancy outcomes. Naturally acquired antibodies (Ab) to placental parasites at delivery have been associated with improved pregnancy outcomes, but Ab levels and how early in p...

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Detalles Bibliográficos
Autores principales: Tutterrow, Yeung Lo, Salanti, Ali, Avril, Marion, Smith, Joseph D., Pagano, Ian S., Ako, Simon, Fogako, Josephine, Leke, Rose G. F., Taylor, Diane Wallace
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383675/
https://www.ncbi.nlm.nih.gov/pubmed/22761948
http://dx.doi.org/10.1371/journal.pone.0040049