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A Daphnane Diterpenoid Isolated from Wikstroemia polyantha Induces an Inflammatory Response and Modulates miRNA Activity

MicroRNAs (miRNAs) are endogenously expressed single-stranded ∼21–23 nucleotide RNAs that inhibit gene expression post-transcriptionally by binding imperfectly to elements usually within the 3′untranslated region (3′UTR) of mRNAs. Small interfering RNAs (siRNAs) mediate site-specific cleavage by bin...

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Detalles Bibliográficos
Autores principales: Khong, Anthony, Forestieri, Roberto, Williams, David E., Patrick, Brian O., Olmstead, Andrea, Svinti, Victoria, Schaeffer, Emily, Jean, François, Roberge, Michel, Andersen, Raymond J., Jan, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383676/
https://www.ncbi.nlm.nih.gov/pubmed/22761847
http://dx.doi.org/10.1371/journal.pone.0039621