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MALDI Imaging Mass Spectrometry for In Situ Proteomic Analysis of Preneoplastic Lesions in Pancreatic Cancer

The identification of new biomarkers for preneoplastic pancreatic lesions (PanINs, IPMNs) and early pancreatic ductal adenocarcinoma (PDAC) is crucial due to the diseasés high mortality rate upon late detection. To address this task we used the novel technique of matrix-assisted laser desorption/ion...

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Detalles Bibliográficos
Autores principales: Grüner, Barbara M., Hahne, Hannes, Mazur, Pawel K., Trajkovic-Arsic, Marija, Maier, Stefan, Esposito, Irene, Kalideris, Evdokia, Michalski, Christoph W., Kleeff, Jörg, Rauser, Sandra, Schmid, Roland M., Küster, Bernhard, Walch, Axel, Siveke, Jens T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383687/
https://www.ncbi.nlm.nih.gov/pubmed/22761793
http://dx.doi.org/10.1371/journal.pone.0039424