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A tethering complex dimer catalyzes trans-SNARE complex formation in intracellular membrane fusion

SNARE complexes mediate membrane fusion in the endomembrane system. They consist of coiled-coil bundles of four helices designated as Qa, Qb, Qc and R. A critical intermediate in the fusion pathway is the trans-SNARE complex generated by the assembly of SNAREs residing in opposing membranes. Mechani...

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Detalles Bibliográficos
Autores principales: Kulkarni, Aditya, Alpadi, Kannan, Namjoshi, Sarita, Peters, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383723/
https://www.ncbi.nlm.nih.gov/pubmed/22754631