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A Transplantable Phosphorylation Probe for Direct Assessment of G Protein-Coupled Receptor Activation

The newly developed multireceptor somatostatin analogs pasireotide (SOM230), octreotide and somatoprim (DG3173) have primarily been characterized according to their binding profiles. However, their ability to activate individual somatostatin receptor subtypes (sst) has not been directly assessed so...

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Detalles Bibliográficos
Autores principales: Kliewer, Andrea, Mann, Anika, Petrich, Aline, Pöll, Florian, Schulz, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383726/
https://www.ncbi.nlm.nih.gov/pubmed/22745760
http://dx.doi.org/10.1371/journal.pone.0039458