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Bronchoalveolar Lavage Enzyme-Linked Immunospot for Diagnosis of Smear-Negative Tuberculosis in HIV-Infected Patients

BACKGROUND: Peripheral blood interferon-gamma release assays (IGRAs) have sub-optimal sensitivity and specificity for diagnosis of active pulmonary tuberculosis (TB). However, assessment of local immune responses has been reported to improve the accuracy of TB diagnosis. METHODS: We enrolled HIV-inf...

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Detalles Bibliográficos
Autores principales: Cattamanchi, Adithya, Ssewenyana, Isaac, Nabatanzi, Rose, Miller, Cecily R., Den Boon, Saskia, Davis, J. Lucian, Andama, Alfred, Worodria, William, Yoo, Samuel D., Cao, Huyen, Huang, Laurence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383728/
https://www.ncbi.nlm.nih.gov/pubmed/22745833
http://dx.doi.org/10.1371/journal.pone.0039838