Endothelial Expression of TGFβ Type II Receptor Is Required to Maintain Vascular Integrity during Postnatal Development of the Central Nervous System

TGFβ signalling in endothelial cells is important for angiogenesis in early embryonic development, but little is known about its role in early postnatal life. To address this we used a tamoxifen inducible Cre-LoxP strategy in neonatal mice to deplete the TypeII TGFβ receptor (Tgfbr2) specifically in...

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Detalles Bibliográficos
Autores principales: Allinson, Kathleen R., Lee, Hye Shin, Fruttiger, Marcus, McCarty, Joseph, Arthur, Helen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383742/
https://www.ncbi.nlm.nih.gov/pubmed/22745736
http://dx.doi.org/10.1371/journal.pone.0039336

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383742/
https://www.ncbi.nlm.nih.gov/pubmed/22745736
http://dx.doi.org/10.1371/journal.pone.0039336

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