Rab14 and Its Exchange Factor FAM116 Link Endocytic Recycling and Adherens Junction Stability in Migrating Cells

Rab GTPases define the vesicle trafficking pathways underpinning cell polarization and migration. Here, we find that Rab4, Rab11, and Rab14 and the candidate Rab GDP-GTP exchange factors (GEFs) FAM116A and AVL9 are required for cell migration. Rab14 and its GEF FAM116A localize to and act on an inte...

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Detalles Bibliográficos
Autores principales: Linford, Andrea, Yoshimura, Shin-ichiro, Bastos, Ricardo Nunes, Langemeyer, Lars, Gerondopoulos, Andreas, Rigden, Daniel J., Barr, Francis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383995/
https://www.ncbi.nlm.nih.gov/pubmed/22595670
http://dx.doi.org/10.1016/j.devcel.2012.04.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383995/
https://www.ncbi.nlm.nih.gov/pubmed/22595670
http://dx.doi.org/10.1016/j.devcel.2012.04.010

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