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BMP8B Increases Brown Adipose Tissue Thermogenesis through Both Central and Peripheral Actions

Thermogenesis in brown adipose tissue (BAT) is fundamental to energy balance and is also relevant for humans. Bone morphogenetic proteins (BMPs) regulate adipogenesis, and, here, we describe a role for BMP8B in the direct regulation of thermogenesis. BMP8B is induced by nutritional and thermogenic f...

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Detalles Bibliográficos
Autores principales: Whittle, Andrew J., Carobbio, Stefania, Martins, Luís, Slawik, Marc, Hondares, Elayne, Vázquez, María Jesús, Morgan, Donald, Csikasz, Robert I., Gallego, Rosalía, Rodriguez-Cuenca, Sergio, Dale, Martin, Virtue, Samuel, Villarroya, Francesc, Cannon, Barbara, Rahmouni, Kamal, López, Miguel, Vidal-Puig, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383997/
https://www.ncbi.nlm.nih.gov/pubmed/22579288
http://dx.doi.org/10.1016/j.cell.2012.02.066