Crystal Structure of the VapBC Toxin–Antitoxin Complex from Shigella flexneri Reveals a Hetero-Octameric DNA-Binding Assembly

Toxin–antitoxin (TA) loci are common in archaea and prokaryotes and allow cells to rapidly adapt to changing environmental conditions through release of active regulators of metabolism. Many toxins are endonucleases that target cellular mRNA and tRNAs, while the antitoxins tightly wrap around the to...

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Detalles Bibliográficos
Autores principales: Dienemann, Christian, Bøggild, Andreas, Winther, Kristoffer S., Gerdes, Kenn, Brodersen, Ditlev E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384007/
https://www.ncbi.nlm.nih.gov/pubmed/22037005
http://dx.doi.org/10.1016/j.jmb.2011.10.024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384007/
https://www.ncbi.nlm.nih.gov/pubmed/22037005
http://dx.doi.org/10.1016/j.jmb.2011.10.024

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