In Vitro Selection of Highly Modified Cyclic Peptides That Act as Tight Binding Inhibitors

[Image: see text] There is a great demand for the discovery of new therapeutic molecules that combine the high specificity and affinity of biologic drugs with the bioavailability and lower cost of small molecules. Small, natural-product-like peptides hold great promise in bridging this gap; however,...

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Detalles Bibliográficos
Autores principales: Guillen Schlippe, Yollete V., Hartman, Matthew C. T., Josephson, Kristopher, Szostak, Jack W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2012
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384292/
https://www.ncbi.nlm.nih.gov/pubmed/22428867
http://dx.doi.org/10.1021/ja301017y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384292/
https://www.ncbi.nlm.nih.gov/pubmed/22428867
http://dx.doi.org/10.1021/ja301017y

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