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Interaction of human telomeric DNA with N-methyl mesoporphyrin IX

The remarkable selectivity of N-methyl mesoporphyrin IX (NMM) for G-quadruplexes (GQs) is long known, however its ability to stabilize and bind GQs has not been investigated in detail. Through the use of circular dichroism, UV-visible spectroscopy and fluorescence resonance energy transfer (FRET) me...

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Detalles Bibliográficos
Autores principales: Nicoludis, John M., Barrett, Steven P., Mergny, Jean-Louis, Yatsunyk, Liliya A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384297/
https://www.ncbi.nlm.nih.gov/pubmed/22362740
http://dx.doi.org/10.1093/nar/gks152