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Engineering naturally occurring trans-acting non-coding RNAs to sense molecular signals
Non-coding RNAs (ncRNAs) are versatile regulators in cellular networks. While most trans-acting ncRNAs possess well-defined mechanisms that can regulate transcription or translation, they generally lack the ability to directly sense cellular signals. In this work, we describe a set of design princip...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384300/ https://www.ncbi.nlm.nih.gov/pubmed/22383579 http://dx.doi.org/10.1093/nar/gks168 |