Neisseria conserved protein DMP19 is a DNA mimic protein that prevents DNA binding to a hypothetical nitrogen-response transcription factor

DNA mimic proteins occupy the DNA binding sites of DNA-binding proteins, and prevent these sites from being accessed by DNA. We show here that the Neisseria conserved hypothetical protein DMP19 acts as a DNA mimic. The crystal structure of DMP19 shows a dsDNA-like negative charge distribution on the...

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Detalles Bibliográficos
Autores principales: Wang, Hao-Ching, Ko, Tzu-Ping, Wu, Mao-Lun, Ku, Shan-Chi, Wu, Hsing-Ju, Wang, Andrew H.-J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384305/
https://www.ncbi.nlm.nih.gov/pubmed/22373915
http://dx.doi.org/10.1093/nar/gks177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384305/
https://www.ncbi.nlm.nih.gov/pubmed/22373915
http://dx.doi.org/10.1093/nar/gks177

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