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The Drosophila 7SK snRNP and the essential role of dHEXIM in development

Regulation of the positive transcription elongation factor, P-TEFb, plays a major role in controlling mammalian transcription and this is accomplished in part by controlled release of P-TEFb from the 7SK snRNP that sequesters the kinase in an inactive state. We demonstrate here that a similar P-TEFb...

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Detalles Bibliográficos
Autores principales: Nguyen, Duy, Krueger, Brian J., Sedore, Stanley C., Brogie, John E., Rogers, Jason T., Rajendra, T. K., Saunders, Abbie, Matera, A. Greg, Lis, John T., Uguen, Patricia, Price, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384314/
https://www.ncbi.nlm.nih.gov/pubmed/22379134
http://dx.doi.org/10.1093/nar/gks191