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Transcriptional provirus silencing as a crosstalk of de novo DNA methylation and epigenomic features at the integration site
The autonomous transcription of integrated retroviruses strongly depends on genetic and epigenetic effects of the chromatin at the site of integration. These effects are mostly suppressive and proviral activity can be finally silenced by mechanisms, such as DNA methylation and histone modifications....
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384319/ https://www.ncbi.nlm.nih.gov/pubmed/22379139 http://dx.doi.org/10.1093/nar/gks197 |