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The role of N-terminus of Plasmodium falciparum ORC1 in telomeric localization and var gene silencing
Plasmodium falciparum origin recognition complex 1 (ORC1) protein has been implicated in DNA replication and silencing var gene family. However, the mechanism and the domain structure of ORC1 related to the regulation of var gene family are unknown. Here we show that the unique N-terminus of PfORC1...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384324/ https://www.ncbi.nlm.nih.gov/pubmed/22379140 http://dx.doi.org/10.1093/nar/gks202 |