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The role of N-terminus of Plasmodium falciparum ORC1 in telomeric localization and var gene silencing

Plasmodium falciparum origin recognition complex 1 (ORC1) protein has been implicated in DNA replication and silencing var gene family. However, the mechanism and the domain structure of ORC1 related to the regulation of var gene family are unknown. Here we show that the unique N-terminus of PfORC1...

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Detalles Bibliográficos
Autores principales: Deshmukh, Abhijit S., Srivastava, Sandeep, Herrmann, Susann, Gupta, Ashish, Mitra, Pallabi, Gilberger, Tim Wolf, Dhar, Suman Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384324/
https://www.ncbi.nlm.nih.gov/pubmed/22379140
http://dx.doi.org/10.1093/nar/gks202