Extracting regulator activity profiles by integration of de novo motifs and expression data: characterizing key regulators of nutrient depletion responses in Streptomyces coelicolor

Determining transcriptional regulator activities is a major focus of systems biology, providing key insight into regulatory mechanisms and co-regulators. For organisms such as Escherichia coli, transcriptional regulator binding site data can be integrated with expression data to infer transcriptiona...

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Detalles Bibliográficos
Autores principales: Iqbal, Mudassar, Mast, Yvonne, Amin, Rafat, Hodgson, David A., Wohlleben, Wolfgang, Burroughs, Nigel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384326/
https://www.ncbi.nlm.nih.gov/pubmed/22406834
http://dx.doi.org/10.1093/nar/gks205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384326/
https://www.ncbi.nlm.nih.gov/pubmed/22406834
http://dx.doi.org/10.1093/nar/gks205

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