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Neural stem cells exposed to BrdU lose their global DNA methylation and undergo astrocytic differentiation
Bromodeoxyuridine (5-bromo-2′-deoxyuridine, BrdU) is a halogenated nucleotide of low toxicity commonly used to monitor DNA replication. It is considered a valuable tool for in vitro and in vivo studies, including the detection of the small population of neural stem cells (NSC) in the mammalian brain...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Oxford University Press
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384327/ https://www.ncbi.nlm.nih.gov/pubmed/22379135 http://dx.doi.org/10.1093/nar/gks207 |