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Neural stem cells exposed to BrdU lose their global DNA methylation and undergo astrocytic differentiation

Bromodeoxyuridine (5-bromo-2′-deoxyuridine, BrdU) is a halogenated nucleotide of low toxicity commonly used to monitor DNA replication. It is considered a valuable tool for in vitro and in vivo studies, including the detection of the small population of neural stem cells (NSC) in the mammalian brain...

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Detalles Bibliográficos
Autores principales: Schneider, Leonid, d’Adda di Fagagna, Fabrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384327/
https://www.ncbi.nlm.nih.gov/pubmed/22379135
http://dx.doi.org/10.1093/nar/gks207