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Proteins and DNA elements essential for the CRISPR adaptation process in Escherichia coli
The clustered regularly interspaced short palindromic repeats and their associated proteins (CRISPR/Cas) constitute a recently identified prokaryotic defense mechanism against invading nucleic acids. Activity of the CRISPR/Cas system comprises of three steps: (i) insertion of alien DNA sequences int...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384332/ https://www.ncbi.nlm.nih.gov/pubmed/22402487 http://dx.doi.org/10.1093/nar/gks216 |