The Caenorhabditis elegans GW182 protein AIN-1 interacts with PAB-1 and subunits of the PAN2-PAN3 and CCR4-NOT deadenylase complexes

GW182 family proteins are essential for miRNA-mediated gene silencing in animal cells. They are recruited to miRNA targets via interactions with Argonaute proteins and then promote translational repression and degradation of the miRNA targets. The human and Drosophila melanogaster GW182 proteins sha...

Descripción completa

Detalles Bibliográficos
Autores principales: Kuzuoğlu-Öztürk, Duygu, Huntzinger, Eric, Schmidt, Steffen, Izaurralde, Elisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384334/
https://www.ncbi.nlm.nih.gov/pubmed/22402495
http://dx.doi.org/10.1093/nar/gks218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384334/
https://www.ncbi.nlm.nih.gov/pubmed/22402495
http://dx.doi.org/10.1093/nar/gks218

Ejemplares similares