Cargando…

The Caenorhabditis elegans GW182 protein AIN-1 interacts with PAB-1 and subunits of the PAN2-PAN3 and CCR4-NOT deadenylase complexes

GW182 family proteins are essential for miRNA-mediated gene silencing in animal cells. They are recruited to miRNA targets via interactions with Argonaute proteins and then promote translational repression and degradation of the miRNA targets. The human and Drosophila melanogaster GW182 proteins sha...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kuzuoğlu-Öztürk, Duygu, Huntzinger, Eric, Schmidt, Steffen, Izaurralde, Elisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384334/ https://www.ncbi.nlm.nih.gov/pubmed/22402495 http://dx.doi.org/10.1093/nar/gks218

Ejemplares similares

The interactions of GW182 proteins with PABP and deadenylases are required for both translational repression and degradation of miRNA targets
por: Huntzinger, Eric, et al.
Publicado: (2013)

GW182 proteins cause PABP dissociation from silenced miRNA targets in the absence of deadenylation
por: Zekri, Latifa, et al.
Publicado: (2013)

The GW/WG repeats of Drosophila GW182 function as effector motifs for miRNA-mediated repression
por: Chekulaeva, Marina, et al.
Publicado: (2010)

miRISC and the CCR4–NOT complex silence mRNA targets independently of 43S ribosomal scanning
por: Kuzuoğlu‐Öztürk, Duygu, et al.
Publicado: (2016)

The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4–NOT deadenylase complex
por: Petit, Alain-Pierre, et al.
Publicado: (2012)

Two PABPC1-binding sites in GW182 proteins promote miRNA-mediated gene silencing
por: Huntzinger, Eric, et al.
Publicado: (2010)

Crystal structure and functional properties of the human CCR4-CAF1 deadenylase complex
por: Chen, Ying, et al.
Publicado: (2021)

Not1 mediates recruitment of the deadenylase Caf1 to mRNAs targeted for degradation by tristetraprolin
por: Sandler, Heike, et al.
Publicado: (2011)

Molecular Basis for poly(A) RNP Architecture and Recognition by the Pan2-Pan3 Deadenylase
por: Schäfer, Ingmar B., et al.
Publicado: (2019)

Trypanosome CNOT10 is essential for the integrity of the NOT deadenylase complex and for degradation of many mRNAs
por: Färber, Valentin, et al.
Publicado: (2013)

The RRM domain in GW182 proteins contributes to miRNA-mediated gene silencing
por: Eulalio, Ana, et al.
Publicado: (2009)

PARN deadenylase is involved in miRNA-dependent degradation of TP53 mRNA in mammalian cells
por: Zhang, Xiaokan, et al.
Publicado: (2015)

The intrinsic structure of poly(A) RNA determines the specificity of Pan2 and Caf1 deadenylases
por: Tang, Terence TL, et al.
Publicado: (2019)

Pan-eukaryote ITS2 homologies revealed by RNA secondary structure
por: Coleman, Annette W.
Publicado: (2007)

A CAF40-binding motif facilitates recruitment of the CCR4-NOT complex to mRNAs targeted by Drosophila Roquin
por: Sgromo, Annamaria, et al.
Publicado: (2017)

GW body disassembly triggered by siRNAs independently of their silencing activity
por: Serman, A., et al.
Publicado: (2007)

The CCR4–NOT Deadenylase Complex Maintains Adipocyte Identity
por: Takahashi, Akinori, et al.
Publicado: (2019)

Regulation of the Drosophila transcriptome by Pumilio and CCR4-NOT deadenylase
por: Haugen, Rebecca J., et al.
Publicado: (2023)

The SMG5–SMG7 heterodimer directly recruits the CCR4–NOT deadenylase complex to mRNAs containing nonsense codons via interaction with POP2
por: Loh, Belinda, et al.
Publicado: (2013)

GW182-Free microRNA Silencing Complex Controls Post-transcriptional Gene Expression during Caenorhabditis elegans Embryogenesis
por: Jannot, Guillaume, et al.
Publicado: (2016)

The activation of the decapping enzyme DCP2 by DCP1 occurs on the EDC4 scaffold and involves a conserved loop in DCP1
por: Chang, Chung-Te, et al.
Publicado: (2014)

Correction: GW182-Free microRNA Silencing Complex Controls Post-transcriptional Gene Expression during Caenorhabditis elegans Embryogenesis
por: Jannot, Guillaume, et al.
Publicado: (2016)

Co-regulation of alternative splicing by diverse splicing factors in Caenorhabditis elegans
por: Barberan-Soler, Sergio, et al.
Publicado: (2011)

Divergent GW182 functional domains in the regulation of translational silencing
por: Yao, Bing, et al.
Publicado: (2011)

A small nucleolar RNA functions in rRNA processing in Caenorhabditis elegans
por: Hokii, Yusuke, et al.
Publicado: (2010)

CAF1 plays an important role in mRNA deadenylation separate from its contact to CCR4
por: Ohn, Takbum, et al.
Publicado: (2007)

The Caenorhabditis elegans intermediate-size transcriptome shows high degree of stage-specific expression
por: Wang, Yunfei, et al.
Publicado: (2011)

Structural identification of conserved RNA binding sites in herpesvirus ORF57 homologs: implications for PAN RNA recognition
por: Tunnicliffe, Richard B, et al.
Publicado: (2019)

TERRA expression is regulated by the telomere-binding proteins POT-1 and POT-2 in Caenorhabditis elegans
por: Manzato, Caterina, et al.
Publicado: (2023)

Alternative splicing of CNOT7 diversifies CCR4–NOT functions
por: Chapat, Clément, et al.
Publicado: (2017)

Molecular basis of differential target regulation by miR-96 and miR-182: the Glypican-3 as a model
por: Jalvy-Delvaille, Sandra, et al.
Publicado: (2012)

CCR4 and CAF1 deadenylases have an intrinsic activity to remove the post-poly(A) sequence
por: Niinuma, Sho, et al.
Publicado: (2016)

Cytoplasmic deadenylase Ccr4 is required for translational repression of LRG1 mRNA in the stationary phase
por: Duy, Duong Long, et al.
Publicado: (2017)

miR-58 family and TGF-β pathways regulate each other in Caenorhabditis elegans
por: de Lucas, María Pilar, et al.
Publicado: (2015)

Defining an evolutionarily conserved role of GW182 in circular RNA degradation
por: Jia, Ruirui, et al.
Publicado: (2019)

The microRNA miR-124 controls gene expression in the sensory nervous system of Caenorhabditis elegans
por: Clark, Alejandra M., et al.
Publicado: (2010)

miRISC recruits decapping factors to miRNA targets to enhance their degradation
por: Nishihara, Tadashi, et al.
Publicado: (2013)

ALG-5 is a miRNA-associated Argonaute required for proper developmental timing in the Caenorhabditis elegans germline
por: Brown, Kristen C., et al.
Publicado: (2017)

Breaking the A chain: regulating mRNAs in development through CCR4 deadenylase
por: Moore, Jocelyn, et al.
Publicado: (2009)

Human Pumilio proteins directly bind the CCR4-NOT deadenylase complex to regulate the transcriptome
por: Enwerem, Isioma I.I., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_s1kmqbo22ltqs55jsv17890one