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CBX4-mediated SUMO modification regulates BMI1 recruitment at sites of DNA damage

Polycomb group (PcG) proteins are involved in epigenetic silencing where they function as major determinants of cell identity, stem cell pluripotency and the epigenetic gene silencing involved in cancer development. Recently numerous PcG proteins, including CBX4, have been shown to accumulate at sit...

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Detalles Bibliográficos
Autores principales: Ismail, Ismail Hassan, Gagné, Jean-Philippe, Caron, Marie-Christine, McDonald, Darin, Xu, Zhizhong, Masson, Jean-Yves, Poirier, Guy G., Hendzel, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384338/
https://www.ncbi.nlm.nih.gov/pubmed/22402492
http://dx.doi.org/10.1093/nar/gks222