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Selective disruption of the DNA polymerase III α–β complex by the umuD gene products

DNA polymerase III (DNA pol III) efficiently replicates the Escherichia coli genome, but it cannot bypass DNA damage. Instead, translesion synthesis (TLS) DNA polymerases are employed to replicate past damaged DNA; however, the exchange of replicative for TLS polymerases is not understood. The umuD...

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Detalles Bibliográficos
Autores principales: Silva, Michelle C., Nevin, Philip, Ronayne, Erin A., Beuning, Penny J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384344/
https://www.ncbi.nlm.nih.gov/pubmed/22406830
http://dx.doi.org/10.1093/nar/gks229