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Unveiling combinatorial regulation through the combination of ChIP information and in silico cis-regulatory module detection

Computationally retrieving biologically relevant cis-regulatory modules (CRMs) is not straightforward. Because of the large number of candidates and the imperfection of the screening methods, many spurious CRMs are detected that are as high scoring as the biologically true ones. Using ChIP-informati...

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Detalles Bibliográficos
Autores principales: Sun, Hong, Guns, Tias, Fierro, Ana Carolina, Thorrez, Lieven, Nijssen, Siegfried, Marchal, Kathleen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384348/
https://www.ncbi.nlm.nih.gov/pubmed/22422841
http://dx.doi.org/10.1093/nar/gks237