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Unveiling combinatorial regulation through the combination of ChIP information and in silico cis-regulatory module detection
Computationally retrieving biologically relevant cis-regulatory modules (CRMs) is not straightforward. Because of the large number of candidates and the imperfection of the screening methods, many spurious CRMs are detected that are as high scoring as the biologically true ones. Using ChIP-informati...
Autores principales: | Sun, Hong, Guns, Tias, Fierro, Ana Carolina, Thorrez, Lieven, Nijssen, Siegfried, Marchal, Kathleen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384348/ https://www.ncbi.nlm.nih.gov/pubmed/22422841 http://dx.doi.org/10.1093/nar/gks237 |
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