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High-throughput single-molecule analysis of DNA–protein interactions by tethered particle motion
Tethered particle motion (TPM) monitors the variations in the effective length of a single DNA molecule by tracking the Brownian motion of a bead tethered to a support by the DNA molecule. Providing information about DNA conformations in real time, this technique enables a refined characterization o...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384352/ https://www.ncbi.nlm.nih.gov/pubmed/22422843 http://dx.doi.org/10.1093/nar/gks250 |