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Follistatin-mediated skeletal muscle hypertrophy is regulated by Smad3 and mTOR independently of myostatin

Follistatin is essential for skeletal muscle development and growth, but the intracellular signaling networks that regulate follistatin-mediated effects are not well defined. We show here that the administration of an adeno-associated viral vector expressing follistatin-288aa (rAAV6:Fst-288) markedl...

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Detalles Bibliográficos
Autores principales: Winbanks, Catherine E., Weeks, Kate L., Thomson, Rachel E., Sepulveda, Patricio V., Beyer, Claudia, Qian, Hongwei, Chen, Justin L., Allen, James M., Lancaster, Graeme I., Febbraio, Mark A., Harrison, Craig A., McMullen, Julie R., Chamberlain, Jeffrey S., Gregorevic, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384410/
https://www.ncbi.nlm.nih.gov/pubmed/22711699
http://dx.doi.org/10.1083/jcb.201109091