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Follistatin-mediated skeletal muscle hypertrophy is regulated by Smad3 and mTOR independently of myostatin
Follistatin is essential for skeletal muscle development and growth, but the intracellular signaling networks that regulate follistatin-mediated effects are not well defined. We show here that the administration of an adeno-associated viral vector expressing follistatin-288aa (rAAV6:Fst-288) markedl...
Autores principales: | Winbanks, Catherine E., Weeks, Kate L., Thomson, Rachel E., Sepulveda, Patricio V., Beyer, Claudia, Qian, Hongwei, Chen, Justin L., Allen, James M., Lancaster, Graeme I., Febbraio, Mark A., Harrison, Craig A., McMullen, Julie R., Chamberlain, Jeffrey S., Gregorevic, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384410/ https://www.ncbi.nlm.nih.gov/pubmed/22711699 http://dx.doi.org/10.1083/jcb.201109091 |
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