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Meiotic cohesin complexes are essential for the formation of the axial element in mice

Cohesin is a conserved multisubunit protein complex that participates in chromosome segregation, DNA damage repair, chromatin regulation, and synaptonemal complex (SC) formation. Yeast, but not mice, depleted of the cohesin subunit Rec8 are defective in the formation of the axial elements (AEs) of t...

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Detalles Bibliográficos
Autores principales: Llano, Elena, Herrán, Yurema, García-Tuñón, Ignacio, Gutiérrez-Caballero, Cristina, de Álava, Enrique, Barbero, José Luis, Schimenti, John, de Rooij, Dirk G., Sánchez-Martín, Manuel, Pendás, Alberto M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384418/
https://www.ncbi.nlm.nih.gov/pubmed/22711701
http://dx.doi.org/10.1083/jcb.201201100