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Meiotic cohesin complexes are essential for the formation of the axial element in mice
Cohesin is a conserved multisubunit protein complex that participates in chromosome segregation, DNA damage repair, chromatin regulation, and synaptonemal complex (SC) formation. Yeast, but not mice, depleted of the cohesin subunit Rec8 are defective in the formation of the axial elements (AEs) of t...
Autores principales: | Llano, Elena, Herrán, Yurema, García-Tuñón, Ignacio, Gutiérrez-Caballero, Cristina, de Álava, Enrique, Barbero, José Luis, Schimenti, John, de Rooij, Dirk G., Sánchez-Martín, Manuel, Pendás, Alberto M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384418/ https://www.ncbi.nlm.nih.gov/pubmed/22711701 http://dx.doi.org/10.1083/jcb.201201100 |
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