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Adipose tissue gene expression analysis reveals changes in inflammatory, mitochondrial respiratory and lipid metabolic pathways in obese insulin-resistant subjects

BACKGROUND: To get insight into molecular mechanisms underlying insulin resistance, we compared acute in vivo effects of insulin on adipose tissue transcriptional profiles between obese insulin-resistant and lean insulin-sensitive women. METHODS: Subcutaneous adipose tissue biopsies were obtained be...

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Detalles Bibliográficos
Autores principales: Soronen, Jarkko, Laurila, Pirkka-Pekka, Naukkarinen, Jussi, Surakka, Ida, Ripatti, Samuli, Jauhiainen, Matti, Olkkonen, Vesa M, Yki-Järvinen, Hannele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384471/
https://www.ncbi.nlm.nih.gov/pubmed/22471940
http://dx.doi.org/10.1186/1755-8794-5-9