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Intergenic Polycomb target sites are dynamically marked by non-coding transcription during lineage commitment

Non-coding (nc) RNAs are involved both in recruitment of vertebrate Polycomb (PcG) proteins to chromatin, and in activation of PcG target genes. Here we investigate dynamic changes in the relationship between ncRNA transcription and recruitment of PcG proteins to chromatin during differentiation. Pr...

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Detalles Bibliográficos
Autores principales: Hekimoglu-Balkan, Betül, Aszodi, András, Heinen, Robert, Jaritz, Markus, Ringrose, Leonie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384584/
https://www.ncbi.nlm.nih.gov/pubmed/22336714
http://dx.doi.org/10.4161/rna.19102