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IL-27 Regulates IL-18 Binding Protein in Skin Resident Cells

IL-18 is an important mediator involved in chronic inflammatory conditions such as cutaneous lupus erythematosus, psoriasis and chronic eczema. An imbalance between IL-18 and its endogenous antagonist IL-18 binding protein (BP) may account for increased IL-18 activity. IL-27 is a cytokine with dual...

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Detalles Bibliográficos
Autores principales: Wittmann, Miriam, Doble, Rosella, Bachmann, Malte, Pfeilschifter, Josef, Werfel, Thomas, Mühl, Heiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384590/
https://www.ncbi.nlm.nih.gov/pubmed/22761702
http://dx.doi.org/10.1371/journal.pone.0038751