An Aqueous Extract of Fagonia cretica Induces DNA Damage, Cell Cycle Arrest and Apoptosis in Breast Cancer Cells via FOXO3a and p53 Expression

BACKGROUND: Plants have proved to be an important source of anti-cancer drugs. Here we have investigated the cytotoxic action of an aqueous extract of Fagonia cretica, used widely as a herbal tea-based treatment for breast cancer. METHODOLOGY/PRINCIPAL FINDINGS: Using flow cytometric analysis of cel...

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Detalles Bibliográficos
Autores principales: Lam, Matt, Carmichael, Amtul R., Griffiths, Helen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384610/
https://www.ncbi.nlm.nih.gov/pubmed/22761954
http://dx.doi.org/10.1371/journal.pone.0040152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384610/
https://www.ncbi.nlm.nih.gov/pubmed/22761954
http://dx.doi.org/10.1371/journal.pone.0040152

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