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Identification of Kinases Regulating Prostate Cancer Cell Growth Using an RNAi Phenotypic Screen
As prostate cancer progresses to castration-resistant disease, there is an increase in signal transduction activity. Most castration-resistant prostate tumors continue to express the androgen receptor (AR) as well as androgen-responsive genes, despite the near absence of circulating androgen in thes...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384611/ https://www.ncbi.nlm.nih.gov/pubmed/22761715 http://dx.doi.org/10.1371/journal.pone.0038950 |