Expression and Cellular Immunogenicity of a Transgenic Antigen Driven by Endogenous Poxviral Early Promoters at Their Authentic Loci in MVA

CD8(+) T cell responses to vaccinia virus are directed almost exclusively against early gene products. The attenuated strain modified vaccinia virus Ankara (MVA) is under evaluation in clinical trials of new vaccines designed to elicit cellular immune responses against pathogens including Plasmodium...

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Detalles Bibliográficos
Autores principales: Orubu, Toritse, Alharbi, Naif Khalaf, Lambe, Teresa, Gilbert, Sarah C., Cottingham, Matthew G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384612/
https://www.ncbi.nlm.nih.gov/pubmed/22761956
http://dx.doi.org/10.1371/journal.pone.0040167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384612/
https://www.ncbi.nlm.nih.gov/pubmed/22761956
http://dx.doi.org/10.1371/journal.pone.0040167

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