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Alteration of EGFR Spatiotemporal Dynamics Suppresses Signal Transduction
The epidermal growth factor receptor (EGFR), which regulates cell growth and survival, is integral to colon tumorigenesis. Lipid rafts play a role in regulating EGFR signaling, and docosahexaenoic acid (DHA) is known to perturb membrane domain organization through changes in lipid rafts. Therefore,...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384615/ https://www.ncbi.nlm.nih.gov/pubmed/22761867 http://dx.doi.org/10.1371/journal.pone.0039682 |