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The Negative Feedback-Loop between the Oncomir Mir-24-1 and Menin Modulates the Men1 Tumorigenesis by Mimicking the “Knudson’s Second Hit”

Multiple endocrine neoplasia type 1 (MEN1) syndrome is a rare hereditary cancer disorder characterized by tumors of the parathyroids, of the neuroendocrine cells, of the gastro-entero-pancreatic tract, of the anterior pituitary, and by non-endocrine neoplasms and lesions. MEN1 gene, a tumor suppress...

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Detalles Bibliográficos
Autores principales: Luzi, Ettore, Marini, Francesca, Giusti, Francesca, Galli, Gianna, Cavalli, Loredana, Brandi, Maria Luisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384621/
https://www.ncbi.nlm.nih.gov/pubmed/22761894
http://dx.doi.org/10.1371/journal.pone.0039767