DOK3 Negatively Regulates LPS Responses and Endotoxin Tolerance

Innate immune activation via Toll-like receptors (TLRs), although critical for host defense against infection, must be regulated to prevent sustained cell activation that can lead to cell death. Cells repeatedly stimulated with lipopolysaccharide (LPS) develop endotoxin tolerance making the cells hy...

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Detalles Bibliográficos
Autores principales: Peng, Qisheng, O’Loughlin, Jason L., Humphrey, Mary Beth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384629/
https://www.ncbi.nlm.nih.gov/pubmed/22761938
http://dx.doi.org/10.1371/journal.pone.0039967

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384629/
https://www.ncbi.nlm.nih.gov/pubmed/22761938
http://dx.doi.org/10.1371/journal.pone.0039967

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