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DOK3 Negatively Regulates LPS Responses and Endotoxin Tolerance
Innate immune activation via Toll-like receptors (TLRs), although critical for host defense against infection, must be regulated to prevent sustained cell activation that can lead to cell death. Cells repeatedly stimulated with lipopolysaccharide (LPS) develop endotoxin tolerance making the cells hy...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384629/ https://www.ncbi.nlm.nih.gov/pubmed/22761938 http://dx.doi.org/10.1371/journal.pone.0039967 |