A Magnetic Bead-Integrated Chip for the Large Scale Manufacture of Normalized esiRNAs

The chemically-synthesized siRNA duplex has become a powerful and widely used tool for RNAi loss-of-function studies, but suffers from a high off-target effect problem. Recently, endoribonulease-prepared siRNA (esiRNA) has been shown to be an attractive alternative due to its lower off-target effect...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Zhao, Huang, Huang, Zhang, Hanshuo, Sun, Changhong, Hao, Yang, Yang, Junyu, Fan, Yu, Xi, Jianzhong Jeff
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384639/
https://www.ncbi.nlm.nih.gov/pubmed/22761791
http://dx.doi.org/10.1371/journal.pone.0039419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384639/
https://www.ncbi.nlm.nih.gov/pubmed/22761791
http://dx.doi.org/10.1371/journal.pone.0039419

Ejemplares similares