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The Rac1 splice form Rac1b promotes K-ras-induced lung tumorigenesis

Rac1b, an alternative splice form of Rac1, has been previously shown to be upregulated in colon and breast cancer cells, suggesting an oncogenic role for Rac1b in these cancers. Our analysis of NSCLC tumor and matched normal tissue samples indicates Rac1b is upregulated in a significant fraction of...

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Detalles Bibliográficos
Autores principales: Zhou, Chun, Licciulli, Silvia, Avila, Jacqueline L., Cho, Miyoung, Troutman, Scott, Jiang, Ping, Kossenkov, Andrew, Showe, Louise C., Liu, Qin, Vachani, Anil, Albelda, Steven M., Kissil, Joseph L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384754/
https://www.ncbi.nlm.nih.gov/pubmed/22430205
http://dx.doi.org/10.1038/onc.2012.99