Inhibition of HSV-1 by chemoattracted neutrophils: supernatants of corneal epithelial cells (HCE) and macrophages (THP-1) treated with virus components chemoattract neutrophils (PMN), and supernatants of PMN treated with these conditioned media inhibit viral growth

The role of PMNs (neutrophils) in corneal herpes was studied using an in vitro system. Human corneal cells (HCE) and macrophages (THP-1) infected with HSV-1 or treated with virus components (DNA or virus immune complexes) released chemokines, which attracted PMNs. Highly reactive oxygen species were...

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Detalles Bibliográficos
Autores principales: Hayashi, Kozaburo, Hooper, Laura C., Okuno, Toshiomi, Takada, Yuichiro, Hooks, John J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2012
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384783/
https://www.ncbi.nlm.nih.gov/pubmed/22527863
http://dx.doi.org/10.1007/s00705-012-1306-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384783/
https://www.ncbi.nlm.nih.gov/pubmed/22527863
http://dx.doi.org/10.1007/s00705-012-1306-y

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