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Ustekinumab in Psoriasis Immunopathology with Emphasis on the Th17-IL23 Axis: A Primer

Psoriasis is a chronic relapsing immunoinflammatory dermatosis that is commonly associated with systemic comorbidities. The pathogenic importance of interleukin (IL)-12 and IL-23 is beyond doubt, as well as the involvement of T helper cells (Th)1 and Th17 cells. There is upregulation of the p40 subu...

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Detalles Bibliográficos
Autores principales: Quatresooz, Pascale, Hermanns-Lê, Trinh, Piérard, Gérald E., Humbert, Philippe, Delvenne, Philippe, Piérard-Franchimont, Claudine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384985/
https://www.ncbi.nlm.nih.gov/pubmed/22754278
http://dx.doi.org/10.1155/2012/147413