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Oridonin Up-regulates Expression of P21 and Induces Autophagy and Apoptosis in Human Prostate Cancer Cells

Background: Oridonin (ORI) could inhibit the proliferation and induce apoptosis in various cancer cell lines. However, the mechanism is not fully understood. Methods: Human prostate cancer (HPC) cells were cultured in vitro and cell viability was detected by the CCK-8 assay. The ultrastructure chang...

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Detalles Bibliográficos
Autores principales: Li, Xiang, Wang, Jiaxiong, Ye, Zaiyuan, Li, Ji-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3385012/
https://www.ncbi.nlm.nih.gov/pubmed/22745580
http://dx.doi.org/10.7150/ijbs.4554