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Arsenic-Transformed Malignant Prostate Epithelia Can Convert Noncontiguous Normal Stem Cells into an Oncogenic Phenotype

Background: Cancer stem cells (CSCs) are likely critical to carcinogenesis, and, like normal stem cells (NSCs), are affected by microenvironmental factors. Malignant cells release extracellular factors, modifying tumor behavior. Inorganic arsenic, a human carcinogen, is associated with an overproduc...

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Detalles Bibliográficos
Autores principales: Xu, Yuanyuan, Tokar, Erik J., Sun, Yang, Waalkes, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3385457/
https://www.ncbi.nlm.nih.gov/pubmed/22472196
http://dx.doi.org/10.1289/ehp.1204987