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Insertions and deletions trigger adaptive walks in Drosophila proteins

Maps that relate all possible genotypes or phenotypes to fitness—fitness landscapes—are central to the evolution of life, but remain poorly known. An insertion or a deletion (indel) of one or several amino acids constitutes a substantial leap of a protein within the space of amino acid sequences, an...

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Detalles Bibliográficos
Autores principales: Leushkin, Evgeny V., Bazykin, Georgii A., Kondrashov, Alexey S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3385466/
https://www.ncbi.nlm.nih.gov/pubmed/22456880
http://dx.doi.org/10.1098/rspb.2011.2571